Pub. Date : 2017 Apr
PMID : 27939799
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The selective P-gp inhibitors (CP100356 and PSC833) enhanced 3-hydroxy-quinidine (3OH-Qi) in jejunum and ileum, while dual inhibitors of P-gp and CYP3A4 (verapamil and ketoconazole) decreased the 3OH-Qi production, despite of the increased intracellular Qi concentration, due to inhibition of CYP3A4. | valspodar | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
2 | The selective P-gp inhibitors (CP100356 and PSC833) enhanced 3-hydroxy-quinidine (3OH-Qi) in jejunum and ileum, while dual inhibitors of P-gp and CYP3A4 (verapamil and ketoconazole) decreased the 3OH-Qi production, despite of the increased intracellular Qi concentration, due to inhibition of CYP3A4. | valspodar | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |