Title : 1α,25-dihydroxyvitamin D inhibits de novo fatty acid synthesis and lipid accumulation in metastatic breast cancer cells through down-regulation of pyruvate carboxylase.

Pub. Date : 2017 Feb

PMID : 27936456






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Constitutive overexpression of PC in MCF10CA1a cells using a pCMV6-PC plasmid inhibited the effect of 1,25(OH)2D on both TAG accumulation and de novo palmitate synthesis from glucose. Glucose pyruvate carboxylase Homo sapiens
2 Constitutive overexpression of PC in MCF10CA1a cells using a pCMV6-PC plasmid inhibited the effect of 1,25(OH)2D on both TAG accumulation and de novo palmitate synthesis from glucose. Glucose pyruvate carboxylase Homo sapiens