Pub. Date : 2017 Jan 22
PMID : 27932243
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of mTOR/eIF4E by anti-viral drug ribavirin effectively enhances the effects of paclitaxel in oral tongue squamous cell carcinoma. | Ribavirin | mechanistic target of rapamycin kinase | Homo sapiens |
| 2 | In this work, we show that ribavirin, an anti-viral drug, effectively augments sensitivity of OTSCC cells to paclitaxel via inhibiting mTOR/eIF4E signaling pathway. | Ribavirin | mechanistic target of rapamycin kinase | Homo sapiens |
| 3 | Mechanistically, ribavirin significantly decreases mTOR/eIF4E signaling pathway in OTSCC cells via suppressing phosphorylation of Akt, mTOR, 4EBP1 and eIF4E. | Ribavirin | mechanistic target of rapamycin kinase | Homo sapiens |
| 4 | Mechanistically, ribavirin significantly decreases mTOR/eIF4E signaling pathway in OTSCC cells via suppressing phosphorylation of Akt, mTOR, 4EBP1 and eIF4E. | Ribavirin | mechanistic target of rapamycin kinase | Homo sapiens |