Pub. Date : 2017 Mar
PMID : 27915415
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Exendin-4 protects HUVECs from tunicamycin-induced apoptosis via inhibiting the IRE1a/JNK/caspase-3 pathway. | Tunicamycin | endoplasmic reticulum to nucleus signaling 1 | Homo sapiens |
| 2 | Similarly, the ratio of p-IRE1alpha/IRE1alpha, p-JNK/JNK and active caspase-3/procaspase-3 were increased by tunicamycin (10 mug/ml); an effect that was counteracted by Exendin-4. | Tunicamycin | endoplasmic reticulum to nucleus signaling 1 | Homo sapiens |
| 3 | Similarly, the ratio of p-IRE1alpha/IRE1alpha, p-JNK/JNK and active caspase-3/procaspase-3 were increased by tunicamycin (10 mug/ml); an effect that was counteracted by Exendin-4. | Tunicamycin | endoplasmic reticulum to nucleus signaling 1 | Homo sapiens |