Pub. Date : 2016
PMID : 27904436
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the present study, we determined the effects of metformin on the levels of pro-inflammatory cytokines (i.e., IL-6, TNF-alpha, and MCP-1) and anti-inflammatory mediator IL-10 in blood and urine of patients with type 2 diabetes. | Metformin | interleukin 6 | Homo sapiens |
| 2 | RESULTS: We found that metformin reduced the levels of IL-6 in blood and MCP-1 in urine, but increased IL-10 levels in blood of patients with type 2 diabetes. | Metformin | interleukin 6 | Homo sapiens |
| 3 | Furthermore, compared to individual drug treatment, metformin significantly reduced the levels of serum IL-6 and TNF-alpha, as well as urine MCP-1. | Metformin | interleukin 6 | Homo sapiens |