Pub. Date : 2017 Apr
PMID : 27889641
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Increased mitochondrial superoxide in the brain, but not periphery, sensitizes mice to angiotensin II-mediated hypertension. | Superoxides | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |
| 2 | Angiotensin II (AngII) elicits the production of superoxide (O2 -) from mitochondria in numerous cell types within peripheral organs and in the brain suggesting a role for mitochondrial-produced O2 - in the pathogenesis of hypertension. | Superoxides | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |
| 3 | Angiotensin II (AngII) elicits the production of superoxide (O2 -) from mitochondria in numerous cell types within peripheral organs and in the brain suggesting a role for mitochondrial-produced O2 - in the pathogenesis of hypertension. | Superoxides | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |
| 4 | Angiotensin II (AngII) elicits the production of superoxide (O2 -) from mitochondria in numerous cell types within peripheral organs and in the brain suggesting a role for mitochondrial-produced O2 - in the pathogenesis of hypertension. | Superoxides | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |
| 5 | Angiotensin II (AngII) elicits the production of superoxide (O2 -) from mitochondria in numerous cell types within peripheral organs and in the brain suggesting a role for mitochondrial-produced O2 - in the pathogenesis of hypertension. | Superoxides | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |
| 6 | Angiotensin II (AngII) elicits the production of superoxide (O2 -) from mitochondria in numerous cell types within peripheral organs and in the brain suggesting a role for mitochondrial-produced O2 - in the pathogenesis of hypertension. | Superoxides | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |
| 7 | Angiotensin II (AngII) elicits the production of superoxide (O2 -) from mitochondria in numerous cell types within peripheral organs and in the brain suggesting a role for mitochondrial-produced O2 - in the pathogenesis of hypertension. | Superoxides | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |
| 8 | Herein, we hypothesized that increased mitochondrial O2 - in the absence of pro-hypertensive stimuli, such as AngII, elevates baseline systemic mean arterial pressure (MAP), and that AngII-mediated hypertension is exacerbated in animals with increased mitochondrial O2 - levels. | Superoxides | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |
| 9 | Herein, we hypothesized that increased mitochondrial O2 - in the absence of pro-hypertensive stimuli, such as AngII, elevates baseline systemic mean arterial pressure (MAP), and that AngII-mediated hypertension is exacerbated in animals with increased mitochondrial O2 - levels. | Superoxides | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |