Pub. Date : 2017 Jul 15
PMID : 27879577
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The potential efficacy of a JAK inhibitor, CP690,550, in neutralizing the effect of IL-6 was evaluated in vitro. | tofacitinib | interleukin 6 | Rattus norvegicus |
| 2 | CONCLUSION: Our results suggest that the IL-6/JAK/STAT3 pathway is involved in the pathogenesis of IVD degeneration and that CP690,550 suppresses the catabolic effect of the IL-6 in the IVD. | tofacitinib | interleukin 6 | Rattus norvegicus |