Title : Menaquinone-4 (vitamin K2) up-regulates expression of human intestinal alkaline phosphatase in Caco-2 cells.

Pub. Date : 2016 Nov

PMID : 27865621






5 Functional Relationships(s)
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1 Menaquinone-4 (MK-4) with 4 isoprene units, vitamin K2, has been shown to induce bone-type ALP activity and osteoblastogenesis in human bone marrow cells. menatetrenone alkaline phosphatase, placental Homo sapiens
2 Menaquinone-4 (MK-4) with 4 isoprene units, vitamin K2, has been shown to induce bone-type ALP activity and osteoblastogenesis in human bone marrow cells. menatetrenone alkaline phosphatase, placental Homo sapiens
3 In this study, we investigated the effects of MK-4 on the level of ALP activity and expression of ALP messenger RNA in the human colon carcinoma cell line Caco-2, which is known to differentiate into small intestinal epithelial cells in vitro. menatetrenone alkaline phosphatase, placental Homo sapiens
4 In this study, we investigated the effects of MK-4 on the level of ALP activity and expression of ALP messenger RNA in the human colon carcinoma cell line Caco-2, which is known to differentiate into small intestinal epithelial cells in vitro. menatetrenone alkaline phosphatase, placental Homo sapiens
5 After treatment with MK-4, there were significant increases in the ALP activities of Caco-2 cells. menatetrenone alkaline phosphatase, placental Homo sapiens