Pub. Date : 2017 Jan
PMID : 27831486
5 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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1 | We investigated the relation between antidepressant-like response to the TCA desipramine using the tail suspension test and saturation binding of [3H]nisoxetine to the norepinephrine transporter (NET), the primary target of desipramine, in juvenile (21 days postnatal [P21]), adolescent (P28), and adult (P90) wild-type (SERT+/+) mice. | Desipramine | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 | Mus musculus | ||
2 | We investigated the relation between antidepressant-like response to the TCA desipramine using the tail suspension test and saturation binding of [3H]nisoxetine to the norepinephrine transporter (NET), the primary target of desipramine, in juvenile (21 days postnatal [P21]), adolescent (P28), and adult (P90) wild-type (SERT+/+) mice. | Desipramine | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 | Mus musculus | ||
3 | We investigated the relation between antidepressant-like response to the TCA desipramine using the tail suspension test and saturation binding of [3H]nisoxetine to the norepinephrine transporter (NET), the primary target of desipramine, in juvenile (21 days postnatal [P21]), adolescent (P28), and adult (P90) wild-type (SERT+/+) mice. | Desipramine | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 | Mus musculus | ||
4 | These data show age-dependent shifts for desipramine to produce antidepressant-like effects that correlate with NET expression in the locus coeruleus and suggest that drugs with NET-blocking activity may be an effective alternative to SSRIs in juveniles. | Desipramine | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 | Mus musculus | ||
5 | These data show age-dependent shifts for desipramine to produce antidepressant-like effects that correlate with NET expression in the locus coeruleus and suggest that drugs with NET-blocking activity may be an effective alternative to SSRIs in juveniles. | Desipramine | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 | Mus musculus |