PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27831486-5 2017 We investigated the relation between antidepressant-like response to the TCA desipramine using the tail suspension test and saturation binding of [3H]nisoxetine to the norepinephrine transporter (NET), the primary target of desipramine, in juvenile (21 days postnatal [P21]), adolescent (P28), and adult (P90) wild-type (SERT+/+) mice. Desipramine 77-88 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 Mus musculus 196-199 27831486-5 2017 We investigated the relation between antidepressant-like response to the TCA desipramine using the tail suspension test and saturation binding of [3H]nisoxetine to the norepinephrine transporter (NET), the primary target of desipramine, in juvenile (21 days postnatal [P21]), adolescent (P28), and adult (P90) wild-type (SERT+/+) mice. Desipramine 224-235 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 Mus musculus 168-194 27831486-5 2017 We investigated the relation between antidepressant-like response to the TCA desipramine using the tail suspension test and saturation binding of [3H]nisoxetine to the norepinephrine transporter (NET), the primary target of desipramine, in juvenile (21 days postnatal [P21]), adolescent (P28), and adult (P90) wild-type (SERT+/+) mice. Desipramine 224-235 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 Mus musculus 196-199 27831486-10 2017 These data show age-dependent shifts for desipramine to produce antidepressant-like effects that correlate with NET expression in the locus coeruleus and suggest that drugs with NET-blocking activity may be an effective alternative to SSRIs in juveniles. Desipramine 41-52 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 Mus musculus 112-115 27831486-10 2017 These data show age-dependent shifts for desipramine to produce antidepressant-like effects that correlate with NET expression in the locus coeruleus and suggest that drugs with NET-blocking activity may be an effective alternative to SSRIs in juveniles. Desipramine 41-52 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 Mus musculus 178-181