Pub. Date : 2017 Jan 1
PMID : 27829579
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Curcumin Suppresses Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells through the Inhibition of Akt/mTOR Pathway. | Curcumin | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Importantly, we found that curcumin reduced Akt, mTOR and P70S6K phosphorylation, effectively suppressing the activity of the Akt/mTOR pathway in HKCs. | Curcumin | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Importantly, we found that curcumin reduced Akt, mTOR and P70S6K phosphorylation, effectively suppressing the activity of the Akt/mTOR pathway in HKCs. | Curcumin | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | Curcumin also promoted HKC proliferation, and antagonized TGF-beta1-driven EMT through the inhibition of Akt/mTOR pathway activity, which may suggest an alternative therapy for renal fibrosis. | Curcumin | AKT serine/threonine kinase 1 | Homo sapiens |