Title : Ginsenoside-Rb1 targets chemotherapy-resistant ovarian cancer stem cells via simultaneous inhibition of Wnt/β-catenin signaling and epithelial-to-mesenchymal transition.

Pub. Date : 2017 Apr 18

PMID : 27825116






1 Functional Relationships(s)
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1 Here we show for the first time, with mechanism-based evidence, that ginsenoside-Rb1, a natural saponin isolated from the rhizome of Panax quinquefolius and notoginseng, exhibits potent cytotoxicity on CSCs. Saponins RB transcriptional corepressor 1 Homo sapiens