Title : Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hot Spots.

Pub. Date : 2017 Feb 1

PMID : 27821479






1 Functional Relationships(s)
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1 Further, deposition of these open chromatin-associated histone marks is dynamic and is manifest at spermatogonia and/or pre-leptotene-stage cells, which facilitates PRDM9 binding and access for Spo11 to direct the formation of DSBs, which are initiated at the leptotene stage. dsbs SPO11 initiator of meiotic double stranded breaks Mus musculus