Title : An active IGF-1R-AKT signaling imparts functional heterogeneity in ovarian CSC population.

Pub. Date : 2016 Nov 7

PMID : 27819360






1 Functional Relationships(s)
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1 Previously we showed that upregulated IGF-1R expression is essential to initiate platinum-taxol resistance at early stage which declines with elevated levels of activated AKT at late resistant stage in ovarian cancer cells. Platinum insulin like growth factor 1 receptor Homo sapiens