Title : Orexin-A Protects Human Neuroblastoma SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Neurotoxicity: Involvement of PKC and PI3K Signaling Pathways.

Pub. Date : 2017 Apr

PMID : 27814668






1 Functional Relationships(s)
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1 Orexin 1 receptor antagonist (SB3344867), PKC, and PI3-kinase (PI3K) inhibitors (chelerythrin and LY294002, respectively) could suppress the orexin-A neuroprotective effect. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Homo sapiens