Pub. Date : 2016 Jul 20
PMID : 27784431
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [Effect of different concentrations of ammonium chloride on expression of hypoxia-inducible factor-1alpha in Chang liver cells]. | Ammonium Chloride | hypoxia inducible factor 1 subunit alpha | Homo sapiens |
| 2 | Objective: To investigate the effect of treatment with different concentrations of ammonium chloride (NH4Cl) on the mRNA and protein expression of hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) in Chang liver cells. | Ammonium Chloride | hypoxia inducible factor 1 subunit alpha | Homo sapiens |
| 3 | Objective: To investigate the effect of treatment with different concentrations of ammonium chloride (NH4Cl) on the mRNA and protein expression of hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) in Chang liver cells. | Ammonium Chloride | hypoxia inducible factor 1 subunit alpha | Homo sapiens |
| 4 | Objective: To investigate the effect of treatment with different concentrations of ammonium chloride (NH4Cl) on the mRNA and protein expression of hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) in Chang liver cells. | Ammonium Chloride | hypoxia inducible factor 1 subunit alpha | Homo sapiens |
| 5 | Objective: To investigate the effect of treatment with different concentrations of ammonium chloride (NH4Cl) on the mRNA and protein expression of hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) in Chang liver cells. | Ammonium Chloride | hypoxia inducible factor 1 subunit alpha | Homo sapiens |
| 6 | Results: Quantitative real-time PCR showed that compared with the control group, the NH4Cl treatment group showed significant increases in the mRNA expression of HIF-1alpha and VEGF across the 5th, 10th, and 15th generations (F = 90976.659/1300.218/1896.800 and 41825.754/2381.321/2591.954, all P < 0.05). | Ammonium Chloride | hypoxia inducible factor 1 subunit alpha | Homo sapiens |
| 7 | The results of immunohistochemistry showed that compared with the control group, the NH4Cl treatment group showed significant increases in the protein expression of HIF-1alpha and VEGF across the 5th, 10th, and 15th generations (F = 376.709/1615.358/1350.120 and 904.789/5105.186/8644.498, all P < 0.05). | Ammonium Chloride | hypoxia inducible factor 1 subunit alpha | Homo sapiens |
| 8 | As was shown by the results of Western blot, compared with the control group, the NH4Cl treatment group showed significant increases in the protein expression of HIF-1alpha and VEGF across the 5th, 10th, and 15th generations (F = 228.499/6051.974/183.219 and 5549.429/40187.665/120982.183, all P < 0.05). | Ammonium Chloride | hypoxia inducible factor 1 subunit alpha | Homo sapiens |