Title : Resveratrol induces cell cycle arrest and apoptosis in human eosinophils from asthmatic individuals.

Pub. Date : 2016 Dec

PMID : 27779703






1 Functional Relationships(s)
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1 In addition, resveratrol was observed to arrest cell cycle progression in G1/S phase by increasing the protein expression levels of p53 and p21, and concurrently reducing the protein expression levels of CDK2, cyclin A and cyclin E. Furthermore, resveratrol treatment significantly induced apoptosis in eosinophils, likely through the upregulation of Bim and Bax protein expression levels and the downregulation of Bcl-2 protein expression. Resveratrol BCL2 apoptosis regulator Homo sapiens