Pub. Date : 2016 Dec
PMID : 27773789
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Decreased thiamine and reduced activity of thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase (OGDH) cause neurodegeneration. | Thiamine Pyrophosphate | oxoglutarate dehydrogenase | Rattus norvegicus |
| 2 | Decreased thiamine and reduced activity of thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase (OGDH) cause neurodegeneration. | Thiamine Pyrophosphate | oxoglutarate dehydrogenase | Rattus norvegicus |
| 3 | According to the data, the astrocytic OGDH may be up-regulated by an increase in intracellular ThDP, while the neuroblastomal OGDH functions at full ThDP saturation. | Thiamine Pyrophosphate | oxoglutarate dehydrogenase | Rattus norvegicus |
| 4 | According to the data, the astrocytic OGDH may be up-regulated by an increase in intracellular ThDP, while the neuroblastomal OGDH functions at full ThDP saturation. | Thiamine Pyrophosphate | oxoglutarate dehydrogenase | Rattus norvegicus |
| 5 | Increased ThDP level in response to the OGDH inhibition presumably up-regulated the enzyme to compensate for a decrease in reducing power which occurred in SP-treated astrocytes. | Thiamine Pyrophosphate | oxoglutarate dehydrogenase | Rattus norvegicus |