Title : Effects of alpha-lipoic acid on expression of iron transport and storage proteins in BV-2 microglia cells.

Pub. Date : 2017 Feb

PMID : 27755990






3 Functional Relationships(s)
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1 RESULTS: We demonstrated that ALA significantly inhibited DMT1 expression, lowered ferritin-light-chain (Ft-L) and ferritin-heavy-chain (Ft-H) content, and had no effect on TfR1 and Fpn1 in BV-2 microglia cells. Thioctic Acid ferritin light polypeptide 1 Mus musculus
2 RESULTS: We demonstrated that ALA significantly inhibited DMT1 expression, lowered ferritin-light-chain (Ft-L) and ferritin-heavy-chain (Ft-H) content, and had no effect on TfR1 and Fpn1 in BV-2 microglia cells. Thioctic Acid ferritin light polypeptide 1 Mus musculus
3 FAC treatment led to a significant increase in Ft-L, Ft-H and Fpn1, and pre-treatment with ALA resulted in a further increase in the contents of Ft-L and Ft-H but not Fpn1 in cells. Thioctic Acid ferritin light polypeptide 1 Mus musculus