Title : Emodin suppresses silica-induced lung fibrosis by promoting Sirt1 signaling via direct contact.

Pub. Date : 2016 Nov

PMID : 27748907






2 Functional Relationships(s)
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1 The levels of TGF-beta1 in the BALF and lung tissue were elevated by silica inhalation, however, they were not affected by either emodin or nicotinamide treatment. Silicon Dioxide transforming growth factor, beta 1 Mus musculus
2 Sirt1-regulated TGF-beta1/Smad signaling was involved in silica inhalation-induced lung fibrosis. Silicon Dioxide transforming growth factor, beta 1 Mus musculus