Title : Human sex hormone-binding globulin as a potential target of alternate plasticizers: an in silico study.

Pub. Date : 2016 Sep 30

PMID : 27719672






2 Functional Relationships(s)
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1 Docking displays showed interactions of alternate plasticizers with 25-30 amino-acid residues of SHBG; 18-20 amino residues overlapped between the natural ligand, DHT, and the three compounds (commonality of 82-91 %). Dihydrotestosterone sex hormone binding globulin Homo sapiens
2 The hydrogen-bonding interaction of the amino-acid residue, Asn-82, of SHBG was also present in displays of DHT and all the three alternate phthalates. Dihydrotestosterone sex hormone binding globulin Homo sapiens