Title : Investigation of the role of XRCC1 genetic polymorphisms in the development of gliomas in a Chinese population.

Pub. Date : 2016 Aug 26

PMID : 27706616






5 Functional Relationships(s)
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1 We observed that the Trp/Trp genotype of XRCC1 Arg194Trp was associated with an increased risk of glioma when compared to the wild-type genotype (odds ratio (OR) = 2.14, 95% confidence interval (CI) = 1.14-3.86, P = 0.03). Tryptophan X-ray repair cross complementing 1 Homo sapiens
2 We observed that the Trp/Trp genotype of XRCC1 Arg194Trp was associated with an increased risk of glioma when compared to the wild-type genotype (odds ratio (OR) = 2.14, 95% confidence interval (CI) = 1.14-3.86, P = 0.03). Tryptophan X-ray repair cross complementing 1 Homo sapiens
3 In the dominant model, we found that the Arg/Trp + Trp/Trp genotype of XRCC1 Arg194Trp could significantly elevate the susceptibility of developing glioma (OR = 1.79, 95%CI = 1.07-0.94). Tryptophan X-ray repair cross complementing 1 Homo sapiens
4 In the dominant model, we found that the Arg/Trp + Trp/Trp genotype of XRCC1 Arg194Trp could significantly elevate the susceptibility of developing glioma (OR = 1.79, 95%CI = 1.07-0.94). Tryptophan X-ray repair cross complementing 1 Homo sapiens
5 In the dominant model, we found that the Arg/Trp + Trp/Trp genotype of XRCC1 Arg194Trp could significantly elevate the susceptibility of developing glioma (OR = 1.79, 95%CI = 1.07-0.94). Tryptophan X-ray repair cross complementing 1 Homo sapiens