Title : Controls of Nuclear Factor-Kappa B Signaling Activity by 5'-AMP-Activated Protein Kinase Activation With Examples in Human Bladder Cancer Cells.

Pub. Date : 2016 Sep

PMID : 27706018






1 Functional Relationships(s)
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1 We found that AICAR or metformin acts as a regulator of LPS/NF-kappaB-or hypoxia/NF-kappaB-mediated cyclooxygenase induction by an AMPK-dependent mechanism with interactions between p65-NF-kappaB phosphorylation and acetylation, including in a human bladder cancer cell line (T24). Metformin nuclear factor kappa B subunit 1 Homo sapiens