Title : Inhibition of M1 macrophage activation in adipose tissue by berberine improves insulin resistance.

Pub. Date : 2016 Dec 1

PMID : 27702567






1 Functional Relationships(s)
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1 In addition, berberine reduced the elevated levels of serum TNF-alpha, IL-6 and MCP-1 and the expressions of TNF-alpha, IL-6 and MCP-1 and attenuated the phosphorylation of JNK and IKKbeta and the expression of NF-kappaB p65 in the obese adipose tissue, Raw264.7 macrophages and 3T3-L1 adipocytes, respectively. Berberine mitogen-activated protein kinase 8 Mus musculus