Pub. Date : 2016 Oct
PMID : 27698824
4 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | miR-101 inhibits glioma cell invasion via the downregulation of COX-2. | mir-101 | prostaglandin-endoperoxide synthase 2 | Homo sapiens | ||
| 2 | The role of miR-101 on COX-2 expression was evaluated by a dual-luciferase reporter assay. | mir-101 | prostaglandin-endoperoxide synthase 2 | Homo sapiens | ||
| 3 | Furthermore, transfection of miR-101 significantly downregulated COX-2 expression in both U373 and U87 glioma cells. | mir-101 | prostaglandin-endoperoxide synthase 2 | Homo sapiens | ||
| 4 | These results indicate that downregulation of miR-101 is involved in the initiation and development of glioma via COX-2 upregulation. | mir-101 | prostaglandin-endoperoxide synthase 2 | Homo sapiens | ||