Title : Repression of Mcl-1 and disruption of the Mcl-1/Bak interaction in myeloma cells couple ER stress to mitochondrial apoptosis.

Pub. Date : 2016 Dec 28

PMID : 27697610






1 Functional Relationships(s)
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1 The decrease in Mcl-1 was associated with protein translation inhibition and identified as a crucial factor in Thapsigargin sensitivity, since it was the only Bcl-2 family protein differentially modified between sensitive and resistant myeloma cells. Thapsigargin BCL2 apoptosis regulator Homo sapiens