Title : Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells.

Pub. Date : 2016 Dec

PMID : 27694802






1 Functional Relationships(s)
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1 These results identify OST inhibition as a potential therapeutic approach for treating receptor-tyrosine-kinase-dependent tumors and provides a chemical probe for reversibly regulating N-linked glycosylation in mammalian cells. Nitrogen dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit Homo sapiens