| Protein Name | dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 1650 |
| Gene Symbol | DDOST |
| UniProt | P39656 (OST48_HUMAN), A0A024RAD5 (A0A024RAD5_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
147
Total Number of Articles : 106 |
Description |
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit |
| Gene Summary |
This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008] |
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