Title : Selective anticancer activity of hydroxyapatite/chitosan-poly(d,l)-lactide-co-glycolide particles loaded with an androstane-based cancer inhibitor.

Pub. Date : 2016 Dec 1

PMID : 27694053






1 Functional Relationships(s)
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1 In this study we utilize an emulsification process and freeze drying to load the composite HAp/Ch-PLGA particles with 17beta-hydroxy-17alpha-picolyl-androst-5-en-3beta-yl-acetate (A), a chemotherapeutic derivative of androstane and a novel compound with a selective anticancer activity against lung cancer cells. androstane reticulon 3 Homo sapiens