Pub. Date : 2016 Nov
PMID : 27666568
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Trimetazidine protects against cardiac ischemia/reperfusion injury via effects on cardiac miRNA-21 expression, Akt and the Bcl-2/Bax pathway. | Trimetazidine | BCL2 associated X, apoptosis regulator | Rattus norvegicus |
| 2 | Furthermore, trimetazidine significantly promoted miRNA-21 expression and phosphorylated-Akt protein expression, and reduced the Bcl-2/Bax ratio in rats following cardiac I/R injury. | Trimetazidine | BCL2 associated X, apoptosis regulator | Rattus norvegicus |
| 3 | In addition, trimetazidine exerts protective effects against cardiac I/R injury through cardiac miRNA-21 expression, Akt, and the Bcl-2/Bax pathway. | Trimetazidine | BCL2 associated X, apoptosis regulator | Rattus norvegicus |