Pub. Date : 2016 Oct 12
PMID : 27665622
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Complexes between K-Ras or the G12X mutants and guanosine 5"-diphosphate (GDP) or GDPnP (a stable GTP analogue) were transferred to the gas phase by nano-electrospray ionization and characterized using UVPD. | Guanosine Diphosphate | KRAS proto-oncogene, GTPase | Homo sapiens |
| 2 | Complexes between K-Ras or the G12X mutants and guanosine 5"-diphosphate (GDP) or GDPnP (a stable GTP analogue) were transferred to the gas phase by nano-electrospray ionization and characterized using UVPD. | Guanosine Diphosphate | KRAS proto-oncogene, GTPase | Homo sapiens |
| 3 | Variations in the efficiencies of backbone cleavages were observed upon substitution of GDPnP for GDP as well as for the G12X mutants relative to wild-type K-Ras. | Guanosine Diphosphate | KRAS proto-oncogene, GTPase | Homo sapiens |
| 4 | An increase in the fragmentation efficiency in the segment containing the first 50 residues was observed for the K-Ras/GDPnP complexes relative to the K-Ras/GDP complexes, whereas a decrease in fragmentation efficiency occurred in the segment containing the last 100 residues. | Guanosine Diphosphate | KRAS proto-oncogene, GTPase | Homo sapiens |