Title : HF-Free Boc Synthesis of Peptide Thioesters for Ligation and Cyclization.

Pub. Date : 2016 Oct 10

PMID : 27654901






1 Functional Relationships(s)
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1 Peptide thioesters give easy, direct, access to cyclic peptides, illustrated by the synthesis of cyclorasin, a KRAS inhibitor. Peptides, Cyclic KRAS proto-oncogene, GTPase Homo sapiens