Title : Exaggerated IL-15 and Altered Expression of foxp3+ Cell-Derived Cytokines Contribute to Enhanced Colitis in Nlrp3-/- Mice.

Pub. Date : 2016

PMID : 27610005






2 Functional Relationships(s)
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1 Colitis was induced in wild-type (WT) and Nlrp3-/- mice by treatment with dextran sulphate sodium (DSS). dss NLR family, pyrin domain containing 3 Mus musculus
2 DSS-treated Nlrp3-/- mice exhibited increased numbers of colonic foxp3+ T cells that expressed significantly lower levels of IL-10 but increased IL-17. dss NLR family, pyrin domain containing 3 Mus musculus