Title : ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion.

Pub. Date : 2016 Sep 7

PMID : 27600527






2 Functional Relationships(s)
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1 Here we report that ATRA, an active metabolite of vitamin A, restores mechanical quiescence in PSCs via a mechanism involving a retinoic acid receptor beta (RAR-beta)-dependent downregulation of actomyosin (MLC-2) contractility. Vitamin A retinoic acid receptor beta Homo sapiens
2 Here we report that ATRA, an active metabolite of vitamin A, restores mechanical quiescence in PSCs via a mechanism involving a retinoic acid receptor beta (RAR-beta)-dependent downregulation of actomyosin (MLC-2) contractility. Vitamin A retinoic acid receptor beta Homo sapiens