Title : 3-Hydroxyflavone inhibits human osteosarcoma U2OS and 143B cells metastasis by affecting EMT and repressing u-PA/MMP-2 via FAK-Src to MEK/ERK and RhoA/MLC2 pathways and reduces 143B tumor growth in vivo.

Pub. Date : 2016 Nov

PMID : 27600294






1 Functional Relationships(s)
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1 3-hydroxyflavone also affected the epithelial-mesenchymal transition (EMT) by down-regulating expressions of Vimentin and alpha-catenin with activation of the transcription factor Slug. 3-hydroxyflavone vimentin Homo sapiens