Title : 15-Deoxy-Δ12,14-prostaglandin J2 stabilizes hypoxia inducible factor-1α through induction of heme oxygenase-1 and direct modification ofprolyl-4-hydroxylase 2.

Pub. Date : 2016 Oct

PMID : 27598034






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Pretreatment with thiol reducing agents blunted 15d-PGJ2-induced HIF-1alpha stabilization, indicative of a cysteine residue as a direct target of 15d-PGJ2. Sulfhydryl Compounds hypoxia inducible factor 1 subunit alpha Homo sapiens