Title : Inhibition of pregnane X receptor pathway contributes to the cell growth inhibition and apoptosis of anticancer agents in ovarian cancer cells.

Pub. Date : 2016 Sep

PMID : 27572875






1 Functional Relationships(s)
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1 Additionally, ketoconazole, a PXR antagonist, suppressed the augmented MDR1 expression and PXR-mediated transactivation by paclitaxel and cisplatin, and enhanced cell growth inhibition and apoptosis in their presence. Cisplatin ATP binding cassette subfamily B member 1 Homo sapiens