Pub. Date : 2016
PMID : 27571418
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition and silencing of HDAC2 and HDAC4 by TSA and siRNA enhanced TGF-beta1-induced EMT in A549 cells. | trichostatin A | histone deacetylase 4 | Homo sapiens |
| 2 | CONCLUSIONS: We showed that EMT is induced by TGF-beta1 in airway epithelial cells and nasal tissue via activation of HDAC2 and HDAC4, and that inhibition of HDAC2 and HDAC4 by TSA reduces TGF-beta1-induced EMT. | trichostatin A | histone deacetylase 4 | Homo sapiens |