Title : AMPK-independent inhibition of human macrophage ER stress response by AICAR.

Pub. Date : 2016 Aug 26

PMID : 27562249






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In a setting of hypoxia-potentiated inflammation induced by SFA palmitate, we found that the AMP-mimetic AMPK activator 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) potently suppressed upregulation of ER stress marker mRNAs and pro-inflammatory cytokines. sfa palmitate protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens