Pub. Date : 2016 Sep
PMID : 27552519
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Puerarin Attenuates N-Methyl-D-aspartic Acid-induced Apoptosis and Retinal Ganglion Cell Damage Through the JNK/p38 MAPK Pathway. | N-Methylaspartate | mitogen-activated protein kinase 8 | Rattus norvegicus |
| 2 | Puerarin pretreatment also effectively inhibited NMDA-induced JNK and p38 phosphorylation in the RGCs, whereas pretreatment with either JNK agonist anisomycin or p38 agonist P79350 could significantly compensate the effects caused by puerarin. | N-Methylaspartate | mitogen-activated protein kinase 8 | Rattus norvegicus |
| 3 | CONCLUSIONS: The present results of this study demonstrated that puerarin protected against NMDA-induced apoptosis and RGCs damage through the JNK/p38 MAPK pathway. | N-Methylaspartate | mitogen-activated protein kinase 8 | Rattus norvegicus |