Title : Effect of 15-Deoxy-△(12,14)-prostaglandin J2 on Expression of Macrophage Migration Inhibitory Factor in Mouse Monocyte/macrophage Cell Line J774A.1.

Pub. Date : 2016 Jun 10

PMID : 27544994






4 Functional Relationships(s)
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1 The effect of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) antagonist GW9662 on the regulation of MIF by 15 d-PGJ2 was observed. 9-deoxy-delta-9-prostaglandin D2 peroxisome proliferator activated receptor gamma Mus musculus
2 The effect of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) antagonist GW9662 on the regulation of MIF by 15 d-PGJ2 was observed. 9-deoxy-delta-9-prostaglandin D2 peroxisome proliferator activated receptor gamma Mus musculus
3 The effects of 15 d-PGJ2 on the nuclear translocation of PPAR-gamma upon LPS challenge were detected via high content screening analysis. 9-deoxy-delta-9-prostaglandin D2 peroxisome proliferator activated receptor gamma Mus musculus
4 Conclusion 15 d-PGJ2 may down-regulate the MIF expression in J774A.1 in a PPAR-gamma-dependent manner. 9-deoxy-delta-9-prostaglandin D2 peroxisome proliferator activated receptor gamma Mus musculus