Title : Imbalance between Glutamate and GABA in Fmr1 Knockout Astrocytes Influences Neuronal Development.

Pub. Date : 2016 Aug 10

PMID : 27517961






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Imbalance between Glutamate and GABA in Fmr1 Knockout Astrocytes Influences Neuronal Development. Glutamic Acid fragile X messenger ribonucleoprotein 1 Mus musculus
2 This neurotoxicity was triggered by an imbalanced release of glutamate and GABA from Fmr1 KO astrocytes. Glutamic Acid fragile X messenger ribonucleoprotein 1 Mus musculus
3 Vigabatrin (VGB), a GABA-T inhibitor, reversed the changes caused by glutamate and GABA release in Fmr1 KO astrocytes and the abnormal behaviors in Fmr1 KO mice. Glutamic Acid fragile X messenger ribonucleoprotein 1 Mus musculus