Pub. Date : 2016 Aug
PMID : 27509335
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Moreover, metformin induces mitochondrial dysfunction and cell death by affecting the level and conformation of Translocase of the Outer Membrane 40 (TOM40), voltage-dependent anion-selective channels 1 (VDAC1) and hexokinase I (HKI), proteins involved in mitochondrial transport of molecules, including Abeta. | Metformin | amyloid beta (A4) precursor protein | Mus musculus |
2 | By using biophysical techniques we found that metformin is able to directly interact with Abeta influencing its aggregation kinetics and features. | Metformin | amyloid beta (A4) precursor protein | Mus musculus |