Title : SIRT1 inhibits inflammatory response partly through regulation of NLRP3 inflammasome in vascular endothelial cells.

Pub. Date : 2016 Sep

PMID : 27505710






2 Functional Relationships(s)
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1 Moreover, SIRT1 expression was reduced in HUVECs stimulated with LPS and ATP. Adenosine Triphosphate sirtuin 1 Homo sapiens
2 SIRT1 activator inhibited the expression of monocyte chemotactic protein-1 (MCP-1) and C-reactive protein (CRP), whereas SIRT1 knockdown resulted in significant increases in MCP-1 and CRP levels in HUVECs stimulated with LPS and ATP. Adenosine Triphosphate sirtuin 1 Homo sapiens