Pub. Date : 2016 Sep
PMID : 27500523
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin. | Metformin | solute carrier family 2 member 2 | Homo sapiens |
| 2 | The C allele of rs8192675 in the intron of SLC2A2, which encodes the facilitated glucose transporter GLUT2, was associated with a 0.17% (P = 6.6 x 10(-14)) greater metformin-induced reduction in hemoglobin A1c (HbA1c) in 10,577 participants of European ancestry. | Metformin | solute carrier family 2 member 2 | Homo sapiens |
| 3 | The C allele of rs8192675 in the intron of SLC2A2, which encodes the facilitated glucose transporter GLUT2, was associated with a 0.17% (P = 6.6 x 10(-14)) greater metformin-induced reduction in hemoglobin A1c (HbA1c) in 10,577 participants of European ancestry. | Metformin | solute carrier family 2 member 2 | Homo sapiens |
| 4 | rs8192675 was the top cis expression quantitative trait locus (cis-eQTL) for SLC2A2 in 1,226 human liver samples, suggesting a key role for hepatic GLUT2 in regulation of metformin action. | Metformin | solute carrier family 2 member 2 | Homo sapiens |
| 5 | rs8192675 was the top cis expression quantitative trait locus (cis-eQTL) for SLC2A2 in 1,226 human liver samples, suggesting a key role for hepatic GLUT2 in regulation of metformin action. | Metformin | solute carrier family 2 member 2 | Homo sapiens |