Protein Name solute carrier family 2 member 2
Organism Homo sapiens
Gene ID 6514
Gene Symbol

SLC2A2

UniProt P11168 (GTR2_HUMAN), Q6PAU8 (Q6PAU8_HUMAN)
Relationships Total Number of functionally related compound(s) : 169
Total Number of Articles : 341
Description

solute carrier family 2 member 2

Gene Summary

This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

synonyms
  • solute carrier family 2, facilitated glucose transporter member 2
  • glucose transporter type 2, liver
  • solute carrier family 2 (facilitated glucose transporter), member 2
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Properties