Protein Name | solute carrier family 2 member 2 |
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Organism | Homo sapiens |
Gene ID | 6514 |
Gene Symbol | SLC2A2 |
UniProt | P11168 (GTR2_HUMAN), Q6PAU8 (Q6PAU8_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
169
Total Number of Articles : 341 |
Description |
solute carrier family 2 member 2 |
Gene Summary |
This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013] |
synonyms |
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Properties | |