Pub. Date : 2016 Nov
PMID : 27497606
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ethanol-induced changes in poly (ADP ribose) polymerase and neuronal developmental gene expression. | Ethanol | poly (ADP-ribose) polymerase family, member 1 | Mus musculus |
| 2 | Poly-ADP Ribose Polymerase (PARP) enzymes are perhaps unique in the field of epigenetics in that they directly participate in histone modifications, transcription factor modifications, DNA methylation/demethylation and are highly inducible by ethanol. | Ethanol | poly (ADP-ribose) polymerase family, member 1 | Mus musculus |
| 3 | Poly-ADP Ribose Polymerase (PARP) enzymes are perhaps unique in the field of epigenetics in that they directly participate in histone modifications, transcription factor modifications, DNA methylation/demethylation and are highly inducible by ethanol. | Ethanol | poly (ADP-ribose) polymerase family, member 1 | Mus musculus |
| 4 | It was our hypothesis that ethanol would induce PARP enzymatic activity leading to alterations in neurodevelopmental gene expression. | Ethanol | poly (ADP-ribose) polymerase family, member 1 | Mus musculus |
| 5 | The current study underscores the importance of PARP in ethanol-induced changes to neurodevelopmental gene expression. | Ethanol | poly (ADP-ribose) polymerase family, member 1 | Mus musculus |