Title : Enhanced effect of κ-carrageenan on TNBS-induced inflammation in mice.

Pub. Date : 2016 Oct

PMID : 27494685






2 Functional Relationships(s)
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1 In addition, kappa-carrageenan, together with TNBS, decreased the enzyme activity of SOD and GSH-px and up-regulated the expression of TLR4, NF-kappaB, p-ERK, p-JNK, p-Jun., IL-8 and MDA in the colonic mucosa. Trinitrobenzenesulfonic Acid nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
2 CONCLUSIONS: kappa-Carrageenan aggravated the TNBS-induced intestinal inflammation, and such an effect could be associated with the oxidative stress and activation of TLR4-NF-kappaB and MAPK/ERK1/2 pathway. Trinitrobenzenesulfonic Acid nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus