Title : Molecular Dynamics Investigation on the Inhibition of MDM2-p53 Interaction by Polyphenols.

Pub. Date : 2013 Feb

PMID : 27481281






1 Functional Relationships(s)
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1 Quercetin and taxifolin bind to p53 binding hydrophobic groove of MDM2, and alter the conformation of groove as evidenced by 65 ns molecular dynamics simulation. Quercetin MDM2 proto-oncogene Homo sapiens