Title : Palmitate-induced ER stress increases trastuzumab sensitivity in HER2/neu-positive breast cancer cells.

Pub. Date : 2016 Jul 27

PMID : 27464732






1 Functional Relationships(s)
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1 In the lipogenic HER2/neu-positive SKBR3 cell line, palmitate induces a G2 phase cell cycle delay and CHOP-dependent apoptosis as well as a partial activation of the ER stress response network via XBP1 and ATF6. Palmitates DNA damage inducible transcript 3 Homo sapiens